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Challenges
(I) Multiple sclerosis: Genuine naked-eye identification
(I-1) Pioneering spinal cord findings
(I-2) Detection of distinctive brain lesions
(I-3) Macropathology: Unexploited key evidence
(II) Histological perspectives
(II-1) Tissue changes in specific lesions
(II-2) Histological lesion categorizations
(II-3) “Selective demyelination”: The facts
(III) The neurologist’s standpoint
(III-1) Classical clinical observations
(III-2) CDMS: Chronically delusive misidentification syndrome
(IV) The specter of the multiple sclerosis agent
(IV-1) Lawless or specific pattern(s) of spread?
(IV-1-a) Multiple sclerosis by blood-borne dissemination?
Character of disseminated myelitis
Spinal multiple sclerosis: Simply cryptogenic disseminated myelitis?
Character of disseminated encephalitis
Cryptic disseminated encephalitis versus cerebral multiple sclerosis
Postvaccinal “multiple sclerosis”
Unexplained encephalomyelitis is not specific multiple sclerosis
(IV-1-b) Inflammatory versus specific plaques
(IV-1-c) Injurious inflammation: The cart before the horse
(IV-2) From randomly spread foci to multiple sclerosis-agent
(IV-3) Looking back in frustration
(V) Lesion explanation in physical terms
(V-1) The dynamics of lesion formation
(V-2) Cause of the injurious impulses
(V-3) The key to decoding multiple sclerosis: Specific data
References
Overview of Plates
© Dr. F. Alfons Schelling, M.D.