Home Table of contents About the author Acknowledgements Contact 

  1. Challenges
  2. (I) Multiple sclerosis: Genuine naked-eye identification
    1. (I-1) Pioneering spinal cord findings
    2. (I-2) Detection of distinctive brain lesions
    3. (I-3) Macropathology: Unexploited key evidence
  3. (II) Histological perspectives
    1. (II-1) Tissue changes in specific lesions
    2. (II-2) Histological lesion categorizations
    3. (II-3) “Selective demyelination”: The facts
  4. (III) The neurologist’s standpoint
    1. (III-1) Classical clinical observations
    2. (III-2) CDMS: Chronically delusive misidentification syndrome
      1. (III-2-a) The first clinical cases
      2. (III-2-b) Mutations of the multiple sclerosis syndrome
      3. (III-2-c) Framing of new clinical criteria
        1. Marburg’s more accommodating criteria
        2. Multiple sclerosis defined by “multiplicity”
        3. Pette: Diagnosis by exclusion and fulminance of attacks
        4. Need for definite “bedside” diagnoses
        5. Schumacher’s “diagnostic time schedules”
        6. The disenchanting truth
  5. (IV) The specter of the multiple sclerosis agent
    1. (IV-1) Lawless or specific pattern(s) of spread?
    2. (IV-2) From randomly spread foci to multiple sclerosis-agent
    3. (IV-3) Looking back in frustration
  6. (V) Lesion explanation in physical terms
    1. (V-1) The dynamics of lesion formation
    2. (V-2) Cause of the injurious impulses
    3. (V-3) The key to decoding multiple sclerosis: Specific data
  7. References
  8. Overview of Plates

    © Dr. F. Alfons Schelling, M.D.